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Issue: Issue 5 (2018) – Supplement 1


Oral Presentation

Multimodal approach in current acute stroke therapy

Author(s):
Ricardo Varela, Daniela Vieira, Cristina Machado, César Nunes, Ricardo Veiga, Egídio Machado, Fernando Silva, João Sargento-Freitas, and Gustavo Santo
Abstract:
Background: Interhospitalar transfer after use of intravenous tissue-type plasminogen activator (tPA) in acute stroke is increasingly frequent. Intra-arterial stroke therapy is progressively challenging demanding an intricated medical and interventional articulation.
Clinical Case: Male patient, 61 yo, mRS 0, with previous history of active smoking, unmedicated hypertension and chronic alcoholism, admitted in a secondary center ER department with a left TACS within 30 min of evolution and scoring 22 in the NIHSS. Workup with head CT and angiogram revealed an ASPECTS of 10 and an occlusion in the M1 segment of the left middle cerebral artery. After interhospitalar stroke protocol activation, the patient initiated tPA (50 min) and was emergently transferred to our center entering the angio-suite after 130 min. Angiography revealed a left internal carotid subocclusive stenosis in addition to the previously identified M1 occlusion. After passing the stenosis, a TICI2b score was achieved using an aspiration device. In the face of early filling delay, it was decided for balloon carotid angioplasty which was successful despite secondary distal embolization determining another aspiration procedure resulting in a final TICI2b score. The patient was submitted to delayed internal carotid stenting after effective antiaggregation at the 10th day, with a final 40% stenosis. No clinical or imagological complications followed the procedures and the patient improved during admission, being discharged after 2 weeks with a NIHSS of 6 and a mRS of 3.
Conclusions: Current acute stroke therapy is quite challenging and demands an effective and organized articulation between the different centers and professionals. The controversy regarding the best clinical approach to tandem pathology is also addressed, further emphasizing the clinical differentiation need in the field.

From the Lisbon Stroke Summit, Lisbon, Portugal. 6–7 April 2018.

International Journal of Clinical Neurosciences and Mental Health 2018; 5(Suppl. 1):O5
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