IJCNMH ARCpublishing

Issue: Issue 2 (2015)

Review Article

Repetitive behaviors in Tourette Syndrome and Obsessive-Compulsive Disorder

Maria Miguel Brenha, Carla Rio, Filipa Sá-Carneiro, and João Massano
Tourette Syndrome (TS) is a neuropsychiatric disorder caracterized by tics that are frequently associated with obsessive-compulsive symptoms (OCS), estimated to be present in 28-63% of patients, though not always sufficient for the diagnosis of an Obsessive-Compulsive Disorder (OCD). Epidemiological, phenomenological and family-genetic studies support an interrelationship between tic disorders and OCD. The repetitive behaviors present in either TS and OCD —tics and compulsions—have been associated with dysfunctional cortico-striato-thalamo-cortical circuits, which is consistent with the hypothesis that OCS and tics might be part of the same spectrum. According to that, OCD with tics assumes an intermediate position between OCD without tics and TS, sharing clinical features with both entities. On the other hand, many studies have reported that tic-related OCD presents specific clinical, neurobiological, genetic and treatment response patterns and TS can be differentiated from OCD subgroups according to obsessive-compulsive symptomatology, presence of sensory phenomena and treatment response. Thus, the phenomenological distinction of repetitive behaviors in patients with TS is important to consider, since the treatment of tics and OCS differs.

Keywords: Tourette Syndrome, Obsessive-Compulsive Disorder, Repetitive Behaviors, Tic, Compulsion, Treatment.

International Journal of Clinical Neurosciences and Mental Health 2015; 2:5

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